CURRICULUM VITAE

HAMID MOBEDI
 

 
Phone: +98-21-44787036
Tel/Fax: +98-21-44580063
E-mail: H.mobedi@ippi.ac.ir
Hmobedi@yahoo.com
 

Mailing Address:
Novel Drug Delivery Systems (NDDS) Department
Iran Polymer and Petrochemical Institute (IPPI)
P.O. Box 14965-115
Tehran, Iran
 
 

Educational Qualifications:
 
Pharm. D. Isfahan University of Medical Sciences, Isfahan, Iran, 1991.
 Ph.D. in Pharmaceutics, Mashhad University of Medical Sciences, Mashhad, Iran, 2000.
 
 

Research Interests:
 

 Controlled drug delivery systems
 In situ forming and injectable drug delivery systems
 Protein and Peptide Formulation for Injectable Drug Delivery Systems
 Biodegradable polymers
 Tissue engineering; in situ forming scaffolds
 Micro/nanosphere & microcapsule production (Electrospray)
 
 

Courses taught:
 

Faculty of Pharmacy, Mashad University
 Pharmaceutical science, for M.Sc students, (1990-1995)
 
 

Iran Polymer and Petrochemical Institute
 Novel Drug Delivery Systems for Ph.D and M.Sc students (2000-2011)

 Polymer Degradation for Ph.D and M.Sc students (2002-2011)
 Protein and Peptide Drug Delivery Systems for Ph.D and M.Sc students
(2003-2011)
 

Faculty of Biomatrial, azad University
 Novel Drug Delivery Systems for Ph.D and M.Sc students (2006-2011)
 

Products Development:
 

 Long-acting injectable 1 month formulations: Variopeptyl (Triptoreline) 3.75
 Long-acting injectable 1 month formulations: Lupromer (Luproreline) 3.75
 Long-acting injectable 1 month formulations: Lupromer (Luproreline) 7.5
 
 

Management Experiences:
 

 Head of Polymer incubator in Iran polymer and petrochemical institute (2003-2006)
 Manager of central Laboratories of Iran polymer and petrochemical institute (2006-2008)
 Head of schematization in Iran polymer and petrochemical institute (2008-2011)
 Manager of knowledge-based “Varian pharmed” company (2004-2015)
 
 

Publications:
 

Journal Articles
 
 

2015
 

Size and morphology controlling of PLGA microparticles produced by electro hydrodynamic atomization
Milad Jafari-Nodoushan, Jalal Barzin, Hamid Mobedi

Polymers for Advanced Technologies, Volume 26, Issue 5, pages 502–513, 2015
 

2014 
 

Aqueous stability of leuprolide acetate: effect of temperature, dissolved oxygen, pH, and complexation with b-cyclodextrin.
M.Rahimi, H. Mobedi, A.Behnamghade

Pharmaceutical Development and Technology, Pages:  1-8, 2014
 
 A novel controlled release drug delivery system for naltrexone administration combined with intermittent morphine to induce antinociception.
A.Norouzi Javidan, F.Yazdi Samadi, S.Latifi, M.Jafari, H.Mobedi

Journal of Drug Delivery Science and Technology, Volume: 24, issue 4, Pages:  413-417, 2014.
 

Investigation of aqueous stability of taxol in different release media.
Mohmad sadegh Amini-fazl, Hamid Mobedi, Jalal Barzin

Drug Development and Industrial Pharmacy, Volume: 40, issue 4, Pages:  419-526, 2014.
 

Incorporation of HAS microparticles within the Taxol-loaded in situ forming PLGA microspheres: synthesis, Characterization and drug release
Mohmad sadegh Amini-fazl, Hamid Mobedi, Jalal Barzin

Polymeric Materials and Polymeric Biomaterials, Volume: 63, issue 12, Pages:  632-640, 2014. 
 

2013
 

Non-isothermal cold crystallization behavior and kinetics of poly (L-lactide): effect of L-lactide dimer
F. Ravari • A. Mashak • M. Nekoomanesh • H. Mobedi
 Polym. Bull. Volume: 70, issue 9, Pages:  2569-2586, 2013.
 

2012
 

Fat-Soluble Vitamins Release Based on Clinoptilolite Zeolite as an Oral Drug Delivery
System
Mehdi Rahimi,; Hamid Mobedi,; Aliasghar Behnamghader,; Alireza Nateghi Baygi,; Houri Mivehchi,; Esmaeil Biazar,

Letters in Drug Design & Discovery,Volume: 9 Pages 213-217, 2012
 

2011
 

Crystalization Behavior of Poly (l-lactide) Films in Presence of Mg (OH)2 and L-Lactide
A.Mashak, H.Mobedi, M.Nekoomanesh,F.Ravari

Iranian Journal of Polymer Science and Technology Volume: 23, issue: 5 Pages: 405-413, 2011
 

L-lactide Additive and In-Vitro Degradation Performance of Poly (l-lactide) films
H.Mobedi, A.Mashak, M. Nekoomanesh, H. Orafai

Iranian Polymer Journal Volume: 20, issue: 3, Pages 237-245, 2011
 

The effect of aliphatic esters on the formation and degradation behavior of PLGA- based in situ forming system
A.Mashak, H.Mobedi, F.Ziaee, M. Nekoomanesh

Polymer Bull Volume: 66, Pages 1063-1073, 2011
 

2010
 

Title: Evaluation of Polymer Concentration Effect on Doxycycline Hyclate Drug Release from in Situ Forming System based on Polylactide-co-Glycolide
H. Farrokhzad, H. Mobedi, J. Barzin, A. Poorkhalil

Iranian Journal of Polymer Science and Technology Volume: 22, issue: 6 Page 497-507, 2010
 

2009
 

Quantitative determination of naltrexone by attenuated total reflectance - FTIR
Spectrometry using partial least squares (PLS) wavelength selection
Khanmohammadi M, Mobedi H, Mobedi E, Kargosha K, Bagheri A, Ghasemi K

Spectroscopy Volume: 23, Pages: 113-121, 2009
 

Influence of Poly (Lactide-Co-Glycolide) Type and Gamma Irradiation on The
Betamethasone Acetate Release from the in situ Forming Systems.
Rafienia M, Emami, S.H, Mirzadeh H, Mobedi H, Karbasi S.

Current Drug Drlivery Volume: 6, Pages: 184-191, 2009
 

Investigation of drug release and H-NMR analysis of the in situ forming systems based on poly (lactide-co-glycolide)
Mohamadnia Z, Ahmadia E, Rafienia M, Mirzadeha H, and Mobedi H

Polymer advanced technologyl, Volume: 20, 48-57, 2009
 

Changes in Morphology of In Situ Forming PLGA Implant Prepared by Different
Polymer Molecular Weight and its Effect on Release Behavior
Astaneh R, Erfan M, Moghimi H, Mobedi H

Journal of pharmaceutical sciences, Volume: 98(1) Pages: 135-45, 2009
 

2008
 

Effects of Ethyl Benzoate on Peformance, Morphology, and Erosion of PLGA Implants
Formed In Situ
Astaneh R, Erfan M, Barzin J, Mobedi H, Moghimi H

Advances in Polymer Thecnology Volume: 27, Pages: 17-26, 2008
 

Ionically cross-linked carrageenan-alginate hydrogel beads
Mohamadnia Z, Zohuriaan-Mehr MJ, Kabiri K, Jamshidi A, Mobedi H,.

Journal of Biomaterials Science-Polymer Edition, Volume: 19 Issue: 1 Pages: 47- 59, 2008
 

Effect of additives on release profile of leuprolide acetate in an in situ forming controlled-release system: In vitro study
Zare M, Mobedi H, Barzin J, et al.

Journal of Applied Polymer Science Volume: 107 Issue: 6 Pages: 3781-3787, 2008
 

Studying the Structural Stability of Leuprolide Acetate after Releasing from Lactide-co-Glycolide Copolymer by Different Spectroscopic Me thods & HTPLC
N. Bahmanyar, K. Haghbeen, A. Jamshidi, H. Mobedi, M. Evini, E. Mobedi

Iranian Polymer Journal,Volume: 17 Issue: 5 Pages: 345-352, 2008
 

2007

Simultaneous determination of levodopa and carbidopa in levodopa-carbidopa tablets by ATR-FTIR Spectrometry
Khanmohammadi M, Mobedi H, Garmarudi AB, et al.

Pharmaceutical Development and Technology Volume: 12 Issue: 6 Pages: 573-580, 2007
 

Full natural hydrogel beads for controlled release of acetate and disodium phosphate derivatives of betamethasone
Mohamadnia Z, Jamshidi A, Mobedi H, et al.

Iranian Polymer Journal Volume: 16 Issue: 10 Pages: 711-718, 2007
 

In vitro evaluation of drug solubility and gamma irradiation on the release of betamethasone under simulated in vivo conditions
Rafienia M, Mirzadeh H, Mobedi H, et al

Journal of Bioactive and Compatible Polymers Volume: 22 Issue: 4 Pages: 443-459, 2007
 

Releasing of leuprolide acetate loaded on an in situ forming system
Mashayekhi R, Mobedi H

International Journal of Artificial Organs Volume: 30 Issue: 8 Pages: 721-72, 2007
 

pH-Sensitive IPN hydrogel beads of carrageenan-alginate for controlled drug delivery
Mohamadnia Z, Zohuriaan-Mehr MJ, Kabiri K, Jamshidi A, Mobedi H.

Journal of Bioactive and Compatible Polymers Volume: 22 Issue: 3 Pages: 342- 356, 2007
 

2006
 

Stability-indicating HPTLC assay for leuprolide acetate
Jamshidi A, Mobedi H, Ahmad-Khanbeigi F

Jpc-Journal of Planar Chromatography-Modern Tlc Volume: 19 Issue: 109 Pages: 223- 227, 2006
 

Formulation of an Injectable Implant for Peptide Delivery & Mechanistic Study of The
Effect of Polymer Molecular Weight on Its Release
Astaneh R, Moghimi H. R, Erfan M, Mobedi H.

Daru Volume: 14 Issue: 2 Pages: 65-70, 2006
 

The effect of additives on naltrexone hydrochloride release and solvent removal rate from an injectable in situ forming PLGA implant
Bakhshi R, Vasheghani-Farahani E, Mobedi H, et al.

Polymers for Advanced Technologies Volume: 17 Issue: 5 Pages: 354-359, 2006
 

Studying the degradation of poly (L-lactide) in presence of magnesium hydroxide
Mobedi H, Nekoomanesh M, Orafaei H, et al.

Iranian Polymer Journal Volume: 15 Issue: 1 Pages: 31-39, 2006
 

2005 AND BEFORE
 

Degradation of poly (D, L-lactide-co-glycolide) 50:50 implant in aqueous medium
Farahani TD, Entezami AA, Mobedi H, et al.

Iranian Polymer Journal Volume: 14 Issue: 8 Pages: 753-763, 2005
 

Ring-opening bulk-melt polymerization of Poly (L-lactide)
Farahani TD, Entezami AA, Mobedi H, et al.

Iran. J. Polym. Sci. Technol Volume: 16 Issue: 4 Pages: 241-248, 2003
 

Development of dendrimer conjugates for drug delivery.
Milhem OM, Mobedi H, Day NH, et al.

Abstracts of Papers of the American Chemical Society Volume: 221 Pages: U417-U417 Part: Part 2 Meeting Abstract: 395-PMSE, 2001
 
 

Conference Articles
 
 

2015
 

Investigation of Effect of Various Drug Loading on Buprenorphine Hydrochloride release from In situ forming Systems based on PLGA polymers
M. Hosseini, H. Mobedi, A. Jamshid

15th Iranian National Congress of Chemical Engineering (IChEC 2015)
 

Formulation of a Polymeric PLGA-Injectable ImplantDelivery System for Controlled Release of Famotidine
F.Banihashemi, H.Mobedi*, J.Barzin

15th Iranian National Congress of Chemical Engineering (IChEC 2015)
 

Morphological investigating of in-situ forming drug delivery systems based on saib-PLGA
S. Bazraee, H. Mobedi, A. Mashak, A. Jamshid

15th Iranian National Congress of Chemical Engineering (IChEC 2015)
 

The use of biocompatible polymer nanoparticles containing magnetic nanoparticles as contrast agents in MRI
A.R. Faramarzi, J. Barzin, H. Mobedi

Nanomedicine in diagnosis and treatment of hard to treat diseases
 

Preparation of biocompatible PLGA fine particles containing magnetite in MRI
A.R. Faramarzi, J. Barzin, H. Mobedi

Nanomedicine in diagnosis and treatment of hard to treat diseases
  

2014
 

Effect of Drug on the Dynamic Mechanical Thermal Properties of Poly (L-lactide)
A. Mashak, H. Mobedi.

11th International Seminar on Polymer Science and Technology
 

Aqueous stability of Leuprolide Acetate: Effect of temperature, dissolved oxygen, pH and complexation with β-cyclodextrin
M. Rahimi, H. Mobedi, A.A. Behnamghader

11th International Seminar on Polymer Science and Technology
 

Effect of surface nodular structure on the PDMS/PES based mambranes pervaporative performances in ethanol/water separation
M. Jafarinasab, J. Barzin, H. Mobedi, H.R. Mortaheb, G.R. Salehi Jouzani, S. Abbasalizadeh

11th International Seminar on Polymer Science and Technology
 

Microsphere embedded matrix: a new method for drug co-therapy
M. Jafari-Nodoushan, J. Barzin, H. Mobedi

11th International Seminar on Polymer Science and Technology
 

Morphological evaluation of in situ forming polymeric scaffold for tissue engineering applications
M.Hajihasani Biouki, H. Mobedi, A.Karkhaneh

11th International Seminar on Polymer Science and Technology
 

Effect of solvent type on in vito Lidocaine HCl release from PLGA-based in situ forming systems
M. Namvar, H.mobedi, A.Mashak

11th International Seminar on Polymer Science and Technology
 

Poly (D, L-lactide-co-glycolide)/ N-methyl-2-pyrrolidone Sol-Gel system for prolonged delivery of Buprenorphine Hydrochloride
M. hosseini, H. mobedi, A. jamshidi

11th International Seminar on Polymer Science and Technology
 

Investigation of effect of various drug loading and addition of a rate modifying agent on Famotidine release from in situ forming implants
F. banihashemi, H. mobedi, J. Barzin

11th International Seminar on Polymer Science and Technology
 

Design of a Combined Morphine Delivery System (Morphine Microsphere- ‎Embedded In-Situ Forming)‎
M. Jafari-Nodoushan, J. Barzin, H. Mobedi

The 1st Middle East (MECRC 2014) & The 6th Iranian Controlled   Release Society ‎Conference (ICRC 2014)
 

Electrospraying: A Tuneable Method of Microparticle Production
M. Jafari-Nodoushan, H. Mobedi, J. Barzin

The 1st Middle East (MECRC 2014) & The 6th Iranian Controlled   Release Society ‎Conference (ICRC 2014)
 

Incorporation of HAS Microparticles within the Taxol-Loaded In situ Forming PLGA ‎Microspheres: Drug Release
M. S. Amini-Fazl, H. Mobedi, J. Barzin, H. Abedini

The 1st Middle East (MECRC 2014) & The 6th Iranian Controlled   Release Society ‎Conference (ICRC 2014)
 

Design of Support Layers based on PES Membrane to Improve the Permeability Performance
M. Jafarinasab, J. Barzin, H. Mobedi, H. R. Mortaheb, G. R. Salehi Jouzani, S. ‎Abbasalizadeh

The 8th International Chemical Engineering Congress & Exhibition (IChEC 2014) 
 

2013
 

Prediction of Crystallization Rate for PLLA/La and PLLA Systems under ‎Isothermal Condition using Dynamic Data
F. Ravari, A. Mashak, M. Nekoomanesh, H. Mobedi

16th Iranian Physical Chemistry Conference
 

Isoconversional Kinetic Analysis of Non-isothermal Cold Crystallization
F. Ravari, A. Mashak, M. Nekoomanesh, H. Mobedi

16th Iranian Physical Chemistry Conference
 

Crystallization Kinetic ofl Poly (L-lactide): Lauritzen-Hoffman Theory
A. Mashak, M. Nekoomanesh, H. Mobedi, F. Ravari

The 16th Iranian Chemistry Congress
 

2012
 

Effect of Surface Roughness on the Prevaporative Performance of PDMS/PES Composite Membranes for Ethanol/ Water Separation
M. Jafarinasab, J. Barzin, H. Mobedi, H. R. Mortaheb, G. Salehi Jouzani, S. Abbasalizadeh

The 14th Iranian National Chemical Engineering Congress (IChEC 2012)
 

A study of the influence of drug loading level on the morphology and burst release in the in situ forming matrices
Mina Hajihasani Biouki, Hamid Mobedi

ISPST2012
                                                                                                                            

Synthesis of Poly hydroxybutyrate-Polyethylene glycol-Folic acid(PHB-PEG-FOL) nanoparticles for targeted drug delivery
M. Rafienia, M. Sattari, H. Mobedi, M. Mahmoudzadeh, A. Fassihi

ISPST2012
 

A study of te influence of drug loading level on the morphology and burst release in the in situ forming matrices
Mina Hajihasani Biouki, Hamid Mobedi

ISPST2012
 

Effect of Polymer Blending on Morphology and Initial Burt Release of an in Situ-Forming Drug Delivery System
M. Jafari-Nodoushan, T. Ebrahimi, H. Mobedi, J. barzin

ISPST2012
 

Controlled Release of Paclitaxel from In situ-Forming PLGA Gel
M. Sadegh Amini-Fazl, H. Mobedi, J. Barzin

ISPST2012             
 

Monitoring the Effect of Flow rate on Size and Morphology of Microspheres Produced by the Means of Electrospraying Method
M. Jafari-Nodoushan, H. Mobedi, J. Barzin

ISPST2012
 

Evaluation of Naltroxone Release Kinetic from In Situ-Forming Drug Delivery System (Investigating the Effect of Polymer End Group Functionality)
M. Jafari-Nodoushan, T. Ebrahimi, J. Barzin, H. Mobedi

ISPST2012             
 

Non-isothermal Cold Crystallization Behavior and Kinetic of Poly(L-lactide): Effect of L-lactide Dimer
A. Mashak, M. Nekoomanesh, H. Mobedi, F. Ravari

ISPST2012
 

2011
 

Organic/Inorganic Hybrid Polymer Nanocomposites based on Polycaprolactone Diacrylate/Polyhedral Oligomeric Silsesquioxane: Synthesis, Characterization and Double Bond Conversion Studies
H. Askari, S. A. Mirmohammadi, M. Imani, M. Ataei, H. Mobedi

The 7th International Chemical Engineering Congress & Exhibition (IChEC 2011)
 

Investigation Expert System Parameters on Modeling Performance of in Situ Forming Controlled Drug Delivery System
A.Haghighat Mesbahi, D. Semnani, J. Barzin, H. Mobedi

PPS 2011
 

Polycaprolactone/Polyhedral Oligomeric Silsesquioxane Hybrid Organic/Inorganic Nanocomposites: Mechanical and Nanomechanical Analyses
H. Askari, S. A. Mirmohammadi, M. Imani, M. Ataei, H. Mobedi

PPS 2011
 

Poly (e-caprolactone diacrylate)/Polyhedral Oligomeric Silsesquioxane Hybrid Organic/Inorganic Nanocomposites: Thermal Studies
H. Askari, S. A. Mirmohammadi, M. Imani, M. Ataei, H. Mobedi

PPS 2011
 

2010
 

Nano-Mechanical Properties & Biomedical Application of Biodegradable Hybrid Organic-Inorganic Nanocomposites Based on Unsaturated Polyester Resins & Polyhedral Oligomeric Silsesquioxane
M. Imani, M. Atai, H. Mobedi, H. Askari

3th Conference on Nanostructures
 

2009
 

Influence of poly(lactide-co-glycolide) type and Gamma irradiation on the betamethasone acetate release from the in situ forming systems
M. rafienia, H. Mirzadeh, H. mobedi, A. jamshidi

16th Iranian Conference of Organic Chemistry
 

H-NMR analysis of biodegradable polymeric systems based on poly (lactide-co-glycolide) and their drug release behaviours
Z. Mohammadnia, E. Ahmadi, H. Mobedi

16th Iranian Conference of Organic Chemistry
 

Crystallization Behavior of Poly (L-lactide) Films Containing Mg (OH) 2 and L-lactide
A. Mashak, M. Nekoomanesh, H. Mobedi, R. Dinarvand

9th International Seminar on Polymer Science and Technology           
 

Photo Cured Nanocomposites based on Poly (hexamethylene carbonate-co-fumarate) and POSS: Thermal and Mechanical Properties
N. Khadem Mohtaram, M. Imani, S. Sharifi, M. Atai, H. Mobedi

9th International Seminar on Polymer Science and Technology           
 

The study of GPC conditions on molecular weight determination of poly (lactide-co-glycolide)
H. Farrokhzad, A. Poorkhalil, J. Barzin, A. Mashak, H. Mobedi

9th International Seminar on Polymer Science and Technology           
 

Modeling of betamethasone release properties from in situ forming systems based on PLGA
S. Sarraf, E. Marzband, H. Mobedi, M. Rafienia, H. Mirzadeh, A. Jamshidi

36th Annual Meeting & Exposition of the controlled Release Society
                                                                                                                            

Influence of L-lactide on the In vitro degradation of poly (L-lactide) films
H. Mobedi, M. Nekoomanesh, H. Orafaei, A. Mashak

36th Annual Meeting & Exposition of the controlled Release Society
 

2008
                                                                                                                            

Characterization of Mixed Poly (lactide-co-glycolide) Injectable Implant for the Three Months Controlled Release of Leuprolide Acetate
M. Enayati, H. Mobedi, H. Mirzadeh, S. Hojati Emami, A. Nateghi

6th World Meeting on Pharmaceutics, Biopharmaceutics & Pharmacetical Technology
                                                                                                                            

Effect of Nano-Hydroxyappatite on Poly (lactide-co-glycolide) Degradation as an In-situ Forming Implant
M. Enayati, H. Mobedi, H. Mirzadeh, S. Hojjati-Emami

35th Annual Meeting & Exposition of the Controlled Release Society
 

2007
                                                                                                                            

Gamma irradiation effects on the release of betamethasone from the biodegradable in situ forming systems
M. Rafienia, H. Mirzadeh, H. Mobedi, A. Jamshidi

International Seminar on Polymer Science & Technology, ISPST 2007
 

Investigation of drug release & H-NMR analysis of the in situ forming systems based on poly (lactide-co-glycolide)
Z. Mohammadnia, E. Ahmadi, M. Rafienia, H. Mobedi, A. Nouri

International Seminar on Polymer Science & Technology, ISPST 2007
 

In vitro Releasing of Leuprolide Acetate Loaded on a PLGA Sol-Gel System
R. Mashayekhi, H. Mobedi

International Seminar on Polymer Science & Technology, ISPST 2007
 

Synthesis & Characterization of Photo Crosslinkable Macromers Based on Polycaprolactone Diacrylate & POSS as Potential Organic-Inorganic Nanocomposites for Biomedical Applications
H. Askari, S. Sharifi, M. Imani, M. Atai, H. Mobedi

21st European Conference on Biomaterials
 

The Effect of Propylene Glycol & Ethyl Acetate on Hydrophobic Naltrexone Released from an In Situ Injectable System
V. Vahabzadeh, H. Mobedi, M. J. Abdekhodaei, H. Mivehchi

3rd Iranian Conference of Novel Drug Delivery Systems     
 

The Type & Loading Effects of Naltrexone on its Release from an In Situ Forming Injectable System
V. Vahabzadeh, H. Mobedi, M. J. Abdekhodaei, H. Mivehchi

3rd Iranian Conference of Novel Drug Delivery Systems
 

A Novel Organic-Inorganic Hybrid Nanocomposite based on Poly (e-Caprolactone diacrylate) & Polyhedrial Oligomeric Silsesquioxane for Biomedical Applications
H. Askari, S. Sharifi, M. Imani, M. Atai, H. Mobedi

7th Int'l Symposium on Fronties in Biomedical Polymers
 

2006
 

Carrageenan-alginate (Calargi) IPNs: The hydrogel bead preparation & characterization
Z. Mohammadnia, M. J. Zohuriaan-Mehr, K. Kabiri, A. Jamshidi, H. mobedi

13th Iranian Seminar of Organic Chemistry
 

Carrageenan-alginate (Calargi) IPN Beads for control release of anti-inflammatory drug
Z. Mohammadnia, M. J. Zohuriaan-Mehr, K. Kabiri, A. Jamshidi, H. mobedi

13th Iranian Seminar of Organic Chemistry
 

Pathological studies of leuprolide acetate loaded on a PLGA sol-gel system
R. Mashayekhi, H. mobedi, H. Mivehchi

10th Iranian Pharmaceutical Sciences Conference (ISPC 2006)
 

Controlled delivery of betamethasone from injectable in situ forming biodegradable PLGH system (in vitro study)
M. Rafienia, H. mirzadeh, H. mobedi, A. jamshidi, S. Bonakdar

10th Iranian Pharmaceutical Sciences Conference (ISPC 2006)
 

Ionically crosslinked alginate/carrageenan beads for control release of betamethasone acetate anti-inflammatory drug
Z. Mohammadnia, M. J. Zohuriaan-Mehr, K. Kabiri, A. jamshidi, H. mobedi

10th Iranian Pharmaceutical Sciences Conference (ISPC 2006)
 

Releasing of leuprolide acetate loaded on a PLGA (50:50) Sol-gel system: Part II. In vivo studies
R. Mashayekhi, H. mobedi, H. Mivehchi

10th Iranian Pharmaceutical Sciences Conference (ISPC 2006)
 

Releasing of leuprolide acetate loaded on a PLGA (50:50) Sol-gel system: Part I. In vitro studies
R. Mashayekhi, H. mobedi, H. Mivehchi

10th Iranian Pharmaceutical Sciences Conference (ISPC 2006)
 

Formulation of an injectable implant for peptide delivery: effect of polymer molecular weight on release, erosion & morphology behavior
Z. Mohammadnia, M. J. Zohuriaan-Mehr, K. Kabiri, A. jamshidi, H. mobedi

33rd Annual Meeting of Exposition of the Controlled Release Society
 

Studying the Effect of Ethyl Heptanoate on Release Profile of Leuprolide Acetate in an in situ Forming Controlled Release System
H. mobedi, M. Zare, A. jamshidi, H. Mivehchi

33rd Annual Meeting of Exposition of the Controlled Release Society
 

In Vitro & In Vivo Comparison of Releasing Leuprolide Acetate Loaded on a PLGA (50:50) In Situ Forming System
R. Mashayekhi, H. mobedi, H. Mivehchi

13th Inter. Pharm. Technol. Symp 
 

2005 and before
 

Study of Poly (D, L lactide-co-glycolide) 50:50 Implant Morphology During Degradation in Aqueous Media
T. Darestani, A. A. Entezami, H. Mobedi, M. Abtahi

Biopolymers& Polymers in Medicine, ISPST 2005, Tehran, Iran
 

Effect of End Group on Degradation of poly (D, L-lactide-Co-glycolide) 50:50 in Aqueous Media
T. Darestani, A. A. Entezami, H. Mobedi, M. Abtahi

Biopolymers& Polymers in Medicine, ISPST 2005, Tehran, Iran
 

NMP Removal from PLGA-Injectable Implant Systems
R. Bakhshi, E. Vasheghani Farahani, H. Mobedi, M. Khakpour

Polymeric Product of Petrochemical Industries, ISPST 2005
 

Solvent Removal from an In-situ Forming Drug Delivery System
R. Bakhshi, E. Vasheghani Farahani, H. Mobedi

The 4th International Postgraduate Research Symposium on Pharmaceutics IPORSIP-2004
 

ATR-FTIR Detection of Naltrexone in Pharmaceuticals
M. Khanmohammadi, H. Mobedi, E. Mobedi, K. Kargosha

13th Iran's Seminar of Analytical Chemistry
 

In-Vitro Degradation of Poly (D, L- Lactide -Co- Glycolide) 50:50 and Release of Naltrexone from PLGA Implants
T. Darestani, Farahani, H. Mobedi, A. Entezami

International Union of Pure and Applied Chemistry World Polymer Congress, MACRO 2004
 

In -Vitro Degradation of Poly (L, D -lactide-co-glycolide 50:50)
T. Darestani, Farahani, H. Mobedi, A. Entezami

Proceedings of the 6th Iranian Seminar on Polymer Science and Technology (ISPST 2003)
 

Effect of Mg (OH)2 on Poly (L,D-lactide-co-glycolide 50:50) Degradation
T. Darestani, A.A. Entezami, H. Mobedi

Proceedings of the 6th Iranian Seminar on Polymer Science and Technology (ISPST 2003)
 

Release of Naltrexone from Poly (L, D-lactide-co-glycolide 50:50) Implant
T. Darestani, A.A. Entezami, H. Mobedi

Proceedings of the 6th Iranian Seminar on Polymer Science and Technology (ISPST 2003)
 

Sustained-Release Biodegradable Implant for Delivery of Naltrexone: Effect of Durg Loading
T. Darestani, Farahani, H. Mobedi, A. Entezami

Proceedings of the 6th Iranian Seminar on Polymer Science and Technology (ISPST 2003)
 

Role of Magnesium Hydroxide on Poly (l-Lactide) Degradation (ii) Microscopy Study
H. Mobedi, M. Nekoomanesh, H. Orafaei

British Pharmaceutical Conference
 

A New HPTLC Method for Determination of Polymer Additives
S. Honary, H. Mobedi, H. Galili                                               

Pharmacy and Pharmaceutical Sciences World Congress 2002, 62nd Congress of FIP
 

Study on Preparation of Intranasal Insulin
H. Mobedi, T. Ghafghazi, M. Anni                                           

Proceeding of 8th Iranian Seminar of Pharmaceutical Sciences (ISPS 8)
 

Role of Magnesium Hydroxide on Poly (L-Lactide) Degradation (I) Effect of Molecular Weight
H. Mobedi, M. Nekoomanesh, H. Orafaei                                

29 Annual Meeting and Exposition of the controlled Release Society
 
 

Research and Technology Projects
 

 

In-situ forming PLA scaffold loaded by chitosan microsphere of Simvastatin enhance bone regeneration
Zurich University, Geneva University, Iran polymer and petrochemical Institute
Nasim Safdarian,Franz Weber, Ivo Krajci, Hamid Mobedi
 

Preparation of Polylactice acid pressable powder for fabricating implantable drug products.
H. mobedi, M. Taghizade, A. Jamshidi
 

Preparation and Investigating of Naloxone implantable products for addiction treatment.
H. mobedi
 

Investigating of effect of additives on the degradation of poly(lactide-glycolide) hydrogels.
H. mobedi, M. Imani, A. Jamshidi
 

Formulation of long-acting Leuprolide Acetate Ampoules (1 months)
H. mobedi, A. Jamshidi
 

Formulation of long-acting injectable Leuprolide Acetate products (3 months)
H. mobedi, A. Jamshidi, J. Barzin
 

Design and Construction of PLGA-based implantable system for Corticosteroid drugs release: in vitro and in vivo studies.
H. mobedi, A. Jamshidi, J. Barzin
 

Providing of general requirement to qualification of central laboratory of Iran polymer and petrochemical institute to achieving ISO/IEC 17025 standard.
H. mobedi, M. Dastmardi
 

Technical development of semi-industrial production of 1 month injectable Leuprolide Acetate products.
H. mobedi, J. Barzin, A. Mashak
 

Stability studies and DMF adjustment for saling long-acting injectable Leuprolide Acetate products.
H. mobedi, M. Imani, A. Jamshidi
 

Investigation of additives on degradation of poly (lactide) film
A. Mashak, H. mobedi, M. Nekoomanesh
 

Investigation of effect of aliphatic esters on degradation of in situ forming systems based on PLGA polymers.
A. Mashak, H. mobedi, F. Ziaee
 

Study of reaction parameters and processing factors on decreasing of residual monomer in acrylic Super absorbents.
S.A. Hashemi, H. mobedi, A. Jamshidi, M.J. Zohourian mehr, K. Kabiri, H. Bouhendi
 

Preparation of silicon coating for comestible drug delivery systems.
A. Rahimi, A. Mashak, H. mobedi, H. Sarvari
 

Production of a drug delivery system for Taxol, anti-cancer drug.
H. Mobedi, J. Barzin, M.Imani
 

Technical development for production of Poly (lactide-co-glycolide) with controllable molecular weight and G/L ratio for drug delivery systems.
F. Shokrollahi, H. Mobedi, Kh. Khodabakhshi.
 

Commercialization of long-acting leuprolide acetate products with biodegradable polymers.
H. Mobedi
 


Patents
 


Preparation of Carrageenan hydrogels for drug delivery.
Iran Patent, No 001962
A .Jamshidi, M.J. Zohourianmehr, Z. Mohammadnia, K. Kabiri, H. Mobedi
 

Utilization of Nano-hydroxyapatite in preparation of biodegradable injectable polymeric systems for prostate cancer treatment.
Iran Patent, No 006238
M. Enayati, H. Mobedi, SH. Hojjati Emami, H. Mirzadeh
 

Preparation of Polylactice acid pressable powder for fabricating implantable drug products.
Iran Patent, No 005067
H. Mobedi, A. Mashak, A. Jamshidi, M. Taghizadeh
 

Optimization of degradation process of L-lactide polymer in presence of L-lactide dimer.
Iran Patent, No 008917
A. Mashak, H. Mobedi, M. Nekoomanesh
 

Drug delivery systems based on natural Zeolite Clinoptilolite-type for vitamin E releasing.
Iran Patent, No 57969
M. Rahimi, A.A. Behnamghader, H. Mobedi et al.
 

Hybrid organic-mineral Biocompatible nano-composites based on unsaturated polyesters and polyhydral oligomeric Siloxane nano-block with Biological applications.
Iran Patent, No 009864
N. Khadem, M. Imani, Sh. Sharifi, H. Mobedi, M, Ataee, IPPI.          
 

Controled release of vitamin K by using of Zeolite, Clinoptilolite-type, in Acidic medium lile the digestive system.
Iran Patent, No 000783
M. Rahimi, A. Nateghi, H. Mobedi, A. Behnamghader, IPPI.
 

Production of long-acting in situ forming Leuprolide Acetate (1 months) in form of tow separated syringe.
Iran Patent, No 62962
H. Mobedi, A. Nateghi, IPPI.
 

Preparation of Polymeric networks based on acrylated diol macromers in novel route with utilization in in situ forming drug delivery systems.
Iran Patent, No 64296
H. Askari, M. Imani, M. Ataee, H. Mobedi, IPPI
 

Hybrid organic-mineral Biocompatible nano-composites based on unsaturated polyesters for releasing drug in recovery of damaged hard tissue.
Iran Patent, No 64297
H. Askari, M. Imani, M. Ataee, H. Mobedi, IPPI
 

Production of pharmaceutical in situ forming nano-composites for Periodontal diseases treatment, in vitro condition.
Iran Patent, No 65351
H. Farrokhzad, H. Mobedi, J. Barzin, A. Pourkhalil, IPPI.
 

Control of degradation process of in situ forming system based on Poly(latic-glycolic) by aliphatic esters.
Iran Patent, No 66521
IPPI, A. Mashak, H. Mobedi, F. Ziyaee.
 

Production of long-acting in situ forming injectable formulation with using ethyl heptanoate.
Iran Patent, No 79782
F. Yazdi, IPPI, M. Jaafari, H. Mobedi, A. Nateghi et al.
 

Production of in situ forming injectable formulation of triptoreline acetate 3.75 mg (1month) with using of biodegradable PLA and PGA polymers.
 Iran Patent, No 80695
A. Nateghi, J. Nazari, M. Jaafari, E. Mobedi, H. Mobedi.
 
 
 

Thesis worked
 

 

 

Grade Year University Supervisiors Student name Title  
M.S C PhD
*   2003 IPPI A.A. Entezami, H. Mobedi, A. Jamshidi T. Darestani Controlled release of naltrexone with biodegradable polymers 1
*   2004 Internatioal university of Imam-Khomeini M.R. Khanmohammadi, H. Mobedi E. Mobedi Evaluation of Levodopa and Carbidopa in Levodopa-C by ATR/FTIR-PLS spectroscopy 2
*   2004 IPPI H. Mobedi, A. Jamshidi M. Zare Investigation of effect of additives on control release of Leuprolide Acetate from lactide -glycolid copolymers. 3
  * 2006 Shahid beheshti, IPPI H.R. Moghimi, H. Mobedi R. Astaneh Preparation of a in situ gelation drug delivery systems and burst release reduction of model drug. 4
*   2006 IPPI, Azad university H. Mobedi R. Mashayekhi Evaluation of leuprolide acetate sol-gel systems in in-vivo conditions 5
*   2007 IPPI H.Mobedi, A.Jamshidi, M.J. Zohourianmehr Z. Mohammadnia Preparation of control release of Corticosteroid drugs based on D,L Alginate – carrageenan and PLGA 6
  * 2007 Amirkabir University, IPPI H. Mirzadeh, H. Mobedi M. Rafienia Preparation of in situ forming drug delivery systems for releasing Corticosteroid drugs based on PLGA  polymers. 7
  * 2008 Azad University of Tehran A.A. Behnamghader, H. Mobedi M. Rahimi Preparation of a drug delivery system based on Zeolites for vitamines release: in vitro study 8
*   2008 IPPI M. Imani, H. Mobedi N. Khadem Investigation of Gentamicin release from biodegradable drug delivery system based on Hybrid organic-mineral nano-composites 9
*   2008 Amirkabir University, IPPI H. Mobedi, Sh. Hojjati Emami M. Enayati Controled release of long acting injectable Leuprolide systems in prostate cancer treatment. 10
*   2008 IPPI M. Imani, H. Mobedi H. Askari Formulation of drug delivery system based on Hybrid organic-mineral nano-composites for releasing drug to Preventing of hard tissue damaging 11
*   2009 Azad University of Tehran H.Mobedi, E. Marzbanrad, M.T. Khorasani S.H. Sarraf Simulation of release profile of Betamethasone from in situ forming drug delivery system based on PLGA by Artificial neural network method 12
*   2009 Azad University of Tehran A. Moti Nasrabadi, H. Mobedi, A.A. Behnamghader S. Tansaz Simulation of affecting parameters on control release of Leuprolide acetate by Artificial neural network 13
*   2009 IPPI H. Mobedi, J.Barzin H. Farrokhzad Preparation and investigation of in situ forming drug delivery system for  Doxycycline drug 14
*   2010 Azad University of Tehran H. Mobedi, M, Hesaraki N. Raadfar Study of degradation process of PLGA polymer affected by Calcium phosphate additives in in-situ forming drug delivery systems 15
*   2010 Azad University of Tehran M. Rafienia, H. Mobedi, A. Fasihi M. Sattari Preparation and evaluation of micro/nanoparticles of Polyhydroxybutyrate and labeled them by Folic acid for Targeting drug delivery to cancer cells 16
*   2010 Azad University of Tehran H. Mobedi A. Madah Development and performing in-vivo study for effectiveness determination of novel product of Leuprolide acetate 17
*   2010 IPPI J. Barzin. H. Mobedi S. Hasheminasab Preparation and characterization of hallow fiber membranes based on ether sulfone in semi-industrial scale and investigating of effective parameters. 18
*   2010 IPPI H. Mobedi, J.Barzin M. Jaafari Nodoushan Designing of a controlled drug delivery system contain naltrexone for pain control 19
*   2010 Azad University of Tehran H. Mobedi, N, Sheykh, A.A. Behnamghader M. Shapooregan Investigation of effect of Gamma irradiation in Sterilizing of in-situ forming novel drug delivery systems 20
*   2010 Azad University of Tehran A.A. Behnamghader, H. Mobedi N. Khalili Preparation of Bioglass/PLGA composites and investigation of its properties for superseded applications. 21
*   2010 Azad University of Tehran H. Mobedi, Gh, Bahrami, M. Ataee F. Yazdi Improvement of release process of drug from in situ forming drug delivery system containing low amount of Naltrexone for pain control by Ethyl heptanoate  additive and its evaluation in in-vitro and in-vivo studies 22
*   2011 IPPI H. Mobedi, J.Barzin N. Malekooti Increasing of stability of Triptoreline acetate with using of Phytic acid in novel drug delivery systems based on PLGA for prostate cancer treatment 23
*   2011 IPPI H. Mobedi, J.Barzin M. Jaafarinasab Designing and making nano filtration membranes based on poly ether sulfone/ poly dimethyl Siloxane for separating of Ethanol and water with evaporation leakage method 24
*   2013 Azad University of Tehran M.T. Khorasani, A. Daliri, H. Mobedi N, Samanipour Producing of Chitosan-Laminin scaffolds for nerve tissue engineering 25
*   2014 IPPI M. Taghizade, H. Mobedi P. Karimshad Synthesis of multi-block acrylate copolymer and investigation of monomer decreasing methods in synthetic co-monomer. 26
  * 2014 IPPI H. Mobedi, J.Barzin M.S Aminifazl Designing and making an in situ forming drug delivery system based on PLGA  polymers for pakli taxole anti-cancer drug 27
*   2014 IPPI H. Mobedi M. Namvar Investigating of releasing of Local anesthetic Lidocaine HCl and base Lidocaine from in situ forming drug delivery systems based on PLGA 28
*   2015 IPPI H. Mobedi, A. Jamshidi M. Hosseini Preparation and evaluation of in situ forming drug delivery systems based on PLGA polymers for Buprenorphine release 29
*   2015 IPPI H. Mobedi, J. Barzin F. Banihashemi Release of Famotidine from in situ forming drug delivery systems based on PLGA polymers 30
*   2015 IPPI F. Shokrollahi, P. Shokrollahi F. Latif Feasibility study of Statin loading in Clay structure and preparation of its composite with PLGA 31